Development of oxacillin resistance in a patient with recurrent Staphylococcus aureus bacteremia.

نویسندگان

  • Eileen M Burd
  • Mohammad Tauqeer Alam
  • Karla D Passalacqua
  • Ameeta S Kalokhe
  • Molly E Eaton
  • Sarah W Satola
  • Colleen S Kraft
  • Timothy D Read
چکیده

Whole-genome sequencing was used to compare longitudinal isolates of Staphylococcus aureus that developed resistance to oxacillin (MIC up to 16 μg/ml). The mecA gene was absent. A novel 5-bp TATCC frameshift insertion in a gene encoding an ABC transporter similar to that of the teichoic acid translocation ATP-binding protein TagH and a 3-bp GCT nonframeshift insertion in the pdhA pyruvate dehydrogenase gene were detected in the oxacillin-resistant isolates.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 52 8  شماره 

صفحات  -

تاریخ انتشار 2014